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Depp's character was previously seen only in a glimpse but the cover of EW magazine gives a full frontal look of the baddie.
Smith's daughter Harley Quinn Smith is also cast for the 'Tusk' follow-up which will center on two minor characters from the first film.
Based on a character created by Kyril Bonfiglioi, Charlie Mortdecai is an art dealer on a quest to recover a stolen painting.
The video gives a sneak peek at Meryl Streep channeling her inner witch, Johnny Depp unleashing his big bad wolf persona, and Anna Kendrick becoming a damsel in distress as Cinderella.
Chris Pine's Prince Charming, Mackenzie Mauzy's Rapunzel, Lilla Crawford's Red Riding Hood, and Meryl Streep's wicked Witch are also featured in the fresh stills.
De Niro is tapped to play opposite Robert Pattinson in the secretive thriller while Depp is in talks to portray the famed magician.
The 'Lone Ranger' actor undergoes dramatic transformation to play the infamous crime kingpin in the biopic directed by Scott Cooper.
When asked if he and her fiancee are expecting a child, the 'Pirates of the Caribbean' star says that their wedding is 'not a shotgun affair.'
The 'Pirates of the Caribbean' star confirms his engagement to Heard in an interview with 'Today' show, saying that Heard is 'a southern belle and sweet as can be, and very good for me.'
Depp confirms his engagement to Amber Heard while in Beijing, saying, 'The fact that I'm wearing a chick's ring on my finger is probably a dead giveaway.'
The 'Fifty Shades of Grey' actress will play the mother of Bulger's baby mama in Scott Cooper-directed 'Black Mass'.
Although his movie 'Lone Ranger' fails to pick up any prize, the actor takes home the first-time Distinguished Artisan Award.
The engaged couple is joined at the special screening in Hollywood by lead actor Kevin Costner and director McG.
After dropping out of the project last year, the 'Alice in Wonderland' actor has now reportedly signed up to play Whitey Bulger.
According to a source, the French actress/singer is 'not bitter' after learning that her former boyfriend got engaged and she '[wishes] them happiness.'