| Rank | Week-1 | Movie Title | Total Gross | ||
| 1 |
|
|
 Iron ManRobert Downey Jr., Terrence Howard
|
$51,190,629 | $177,825,024 |
| 2 |
|
|
What Happens in Vegas...Cameron Diaz, Ashton Kutcher
|
$20,172,474 | $20,172,474 |
| 3 |
|
|
Speed RacerEmile Hirsch, Christina Ricci
|
$18,561,337 | $18,561,337 |
| 4 |
 |
|
Made of HonorPatrick Dempsey, Michelle Monaghan
|
$8,116,323 | $26,791,494 |
| 5 |
|
|
Baby MamaTina Fey, Amy Poehler
|
$6,225,790 | $40,836,370 |
| 6 |
|
|
Forgetting Sarah MarshallJason Segel, Kristen Bell
|
$3,837,240 | $50,781,745 |
| 7 |
|
|
Harold & Kumar Escape from Guantanamo BayKal Penn, John Cho
|
$3,106,424 | $30,667,308 |
| 8 |
|
|
The Forbidden KingdomJet Li, Jackie Chan
|
$2,169,323 | $48,530,104 |
| 9 |
|
|
Nim's IslandAbigail Breslin, Jodie Foster
|
$1,463,622 | $44,395,857 |
| 10 |
|
|
Prom NightBrittany Snow, Johnathon Schaech
|
$1,012,986 | $42,785,107 |
| 11 |
|
|
RedbeltChiwetel Ejiofor, Alice Braga
|
$1,012,435 | $1,109,674 |
| 12 |
|
|
21Jim Sturgess, Kate Bosworth
|
$851,385 | $80,434,035 |
| 13 |
 |
|
The VisitorRichard Jenkins, Haaz Sleiman
|
$729,212 | $2,475,492 |
| 14 |
|
|
Horton Hears a Who!Jim Carrey, Steve Carell
|
$605,347 | $150,699,120 |
| 15 |
|
|
88 MinutesAl Pacino, Alicia Witt
|
$534,104 | $16,460,014 |
| 16 |
|
|
Drillbit TaylorOwen Wilson, Leslie Mann
|
$508,095 | $31,760,807 |
| 17 |
|
|
Then She Found MeHelen Hunt, Bette Midler
|
$467,577 | $890,591 |
| 18 |
|
|
Young@HeartJim Armenti, William E. Arnold Jr.
|
$388,928 | $1,444,646 |
| 19 |
|
|
10,000 B.C.Steven Strait, Camilla Belle
|
$347,407 | $94,042,448 |
| 20 |
|
|
BhoothnathAmitabh Bachchan, Juhi Chawla
|
$330,246 | $330,246 |
