An 8-year-old bipolar boy whose life is consumed by a video game he plays in his head is admitted to Wharton Memorial for an accident involving a knife. When it turns out the accident was really a suicide attempt, Jack must try to get inside the little boy's head to find out what is triggering his life-threatening rages. But when the boy bolts from the psych ward, Jack must try to save him by engaging him in his own mind game. Meanwhile, Nora discovers her teenage daughter is posting provocative pictures of herself on the Internet, and Jack continues to search for his mentally ill sister who he believes is living on the streets of L.A.