Sam (Jared Padalecki) and Dean (Jensen Ackles) meet Gordon (guest star Sterling K. Brown), a fellow demon hunter who has been systematically killing vampires in a small town, and Dean immediately bonds with the older man.

However, after Sam meets with the lead vampire (guest star Amber Benson) and discovers they are actually peaceful creatures who survive on cattle blood, he decides not all supernatural beings are evil and forces Dean to choose whether he will side with Sam or Gordon.