Steve Howell is found stabbed to death in his hotel room. The primary suspect is Christina Dodd who was lying next to him in bed unharmed, with no recollection of what happened. While a drug test proves Steve drugged Christina with GHB, the CSIs learn she is not as innocent as she claims to be. The hotel concierge attests Christina was consenting in the act, which forces her confession of being a housewife who recently started sleeping with men for money. And when evidence leads to another housewife, Lisa Radley, with a similar story involving Steve, the team makes a shocking discovery: Steve was hired by a madam to seduce, drug, and rob the "soccer moms" in an effort to scare them off and keep them from cutting into her profits. Since Steve targeted married women, the team must look not only at his scorned one night stands but also their husbands to find the killer.