Down on his luck and drowning in debt, charismatic but impulsive gambler Gerry (Ben Mendelsohn) sees a potential lifeline in the smooth-talking, high-stakes poker player Curtis (Ryan Reynolds). Despite their contrasting personalities—Gerry is a weary romantic, while Curtis is a reckless thrill-seeker—they form an unlikely partnership fueled by a shared belief in luck and second chances. Together, they embark on a road trip from Iowa to New Orleans, chasing a legendary high-stakes poker game that could change everything. Along the way, they encounter a series of colorful characters, including the pragmatic and kind-hearted Simone (Sienna Miller), who offers Gerry a glimpse of a life beyond the felt. Directed with a keen eye for atmosphere by Ryan Fleck and Anna Boden, this drama explores the seductive pull of risk and the desperate hope that the next big win will solve all problems. As their journey becomes a haze of booze, women, and ever-escalating bets, the duo must confront whether their bond is true friendship or just another losing hand.