Grey's Anatomy (2005-now)

Cast and Crew

Main Cast

• Ellen Pompeo as Dr. Meredith Grey
• Sandra Oh as Dr. Cristina Yang
• Katherine Heigl as Dr. Isobel "Izzie" Stevens
• Patrick Dempsey as Dr. Derek Shepherd
• Justin Chambers as Dr. Alex Karev
• T.R. Knight
• Chandra Wilson
• Kate Walsh as Dr. Addison Montgomery-Shepherd
• Isaiah Washington as Dr. Preston Burke
• James Pickens Jr.
• Sara Ramirez as Dr. Callie Torres
• Eric Dane

The Story

Season 1

Meredith Grey, the daughter of the once-renowned surgeon Ellis Grey, becomes an intern at the Seattle Grace Hospital. She meets fellow interns Cristina Yang, Isobel "Izzie" Stevens, and George O'Malley who would be her closest friends during the intern program. Other characters include Dr. Miranda Bailey, nicknamed "Nazi" due to her "tough love" capability; Alex Karev, an intern who is not very popular with the others (especially Izzie); and renowned surgeons Dr. Derek Shepherd and Dr. Preston Burke. The chief of surgery is Richard Webber, who was once more than close friends with Meredith's mother.

The season chronicles the first few months of the internship program and the day-to-day life of a surgical intern. Recurring plots include Meredith's battle to keep her mother's Alzheimer's disease a secret and her relationship with Dr. Shepherd. Others include George's infatuation with Meredith and a power struggle between Dr. Burke and Dr. Shepherd in the hospital. The season's end introduces Kate Walsh as Dr. Addison Montgomery-Shepherd, Derek's estranged wife. Although for other areas where the season was aired, the season end is Meredith waiting.

Season 2

The second season focuses on Meredith and Derek's relationship, which came to an abrupt halt when it was revealed that Derek is married to surgeon Addison Montgomery. Izzie and Alex embark on a relationship of their own (although cut short when Izzie falls for heart patient Denny Duquette), as do Cristina Yang and Preston Burke. Doctor Baily becomes pregnant, and more is revealed about her personal life. On some of the weeks airing after its highly-watched February 5, 2006 post-Super Bowl episode, the program attracted more viewers than its lead-in, Desperate Housewives.

Once the second season ended on May 15, 2006, the show had two previously recurring actors, Sarah Ramirez (Callie Torres) and Eric Dane (Mark Sloan), join the regular cast. The series' opening credit sequence was also dropped by the last half of the second season, replaced by a title card displayed at the end of the first act and credits displayed over the opening of the second act of each episode.

Season 3

As the season came to a close, Burke called off his wedding to Cristina at the church, Chief Webber stayed on as the Chief of Surgery, Callie was appointed Chief Resident, and George learned he failed the final intern exam. The relationship between Derek and Meredith, as well as the triangle between Callie, George, and Izzie were left unresolved. Addison decides to start a new life in Los Angeles in the spin-off Private Practice.

Season 4

The character Dr. Erica Hahn (The Silence of the Lambs fame actress Brooke Smith) joined the main cast, reprising her antagonizing role in the season's fifth episode. She replaces Preston Burke as head of Cardiothoracics. Upon her return, she makes Sandra Oh's character, Cristina Yang work harder for her success in Cardiothoracics and initially served as a new love interest for Eric Dane's Mark Sloan.

It was reported that a new male character would be introduced. This character would somehow be in "competition" with Dr. Derek Shepherd. Fourth season guest stars included former Gilmore Girls actor Edward Herrmann who appeared in three episodes. Seth Green of Buffy the Vampire Slayer fame guest starred in a two-part episode. Lauren Stamile plays a scrub nurse named Rose, who became a potential love interest for Derek. Dawson's Creek alumnus Joshua Jackson was scheduled to make his return to television in a multi-episode arc as a doctor with his first appearance in the season's eleventh episode. Jackson's appearance was cancelled due to the 2007-2008 Writers Guild of America strike. Kate Walsh returned as Dr. Addison Montgomery on May 1.

Meredith having a huge breakthrough with her personal life including Derek and her mother. Derek also realized he continually failed Meredith. Meredith and Derek preformed clinical trials on patients with brain tumors. They lost all of their patients except for one whose boyfriend died just before her life saving surgery. After finally succeeding, Meredith finally took a risk and reunited with Derek. Almost all the cast had a kiss, including Meredith and Derek, George and Lexie, Richard and Adelle, Alex and Izzie, and, Erica and Callie. To prepare for the lesbian story line, which will continue in season five, Grey's consulted with GLAAD. We also learned about Alex's needy mother and part of his past. After Meredith and Derek's resumption of their relationship, Derek left to break up with Rose, his girlfriend who had come between the two previously.

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Episode 5.10 Promo

Episode 5.09 Promo

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