Anna (guest star Julie McNiven) remembers her past and Sam (Jared Padalecki) and Dean (Jensen Ackles) finally understand why Castiel (guest star Misha Collins) and Uriel (guest star Robert Wisdom) want her dead.

However, they disagree with the angels' orders and try to help Anna restore an important part of her past so she can be saved.

Meanwhile, Alastair (guest star Mark Rolston) and his demons continue to close in on Anna and the brothers.