When the kids start to show complacency, Will instills some rivalry to fire them up. He divides the glee club into boys against girls for a mashup competition. Winner gets to choose the song for Sectionals.
Sue notices that Quinn's leg has quivered in her cheerleading formation. Quinn claims that she's tired from glee club. So Sue decides that she must destroy Will in order to get rid of the club. Sue tells Terri that Emma is after her husband, encouraging Terri to apply for the school nurse position even though she has no experience. Terri needs to keep an eye on Will.
With football practice, glee rehearsal, and a pregnant girlfriend, Finn is exhausted. Puck advises him to go to the school nurse for a nap. Terri, in her new job, gives Finn pseudoephedrine pills to wake him up. She explains that it's like a vitamin. A wired Finn returns to the rehearsal room pumped up to work on the mashup. He gives his new "vitamins" to the other guys.
Rachel is insistent that the girls prepare for their mashup, but the others don't feel they need to worry about beating the boys. The guys give an amazing and energized performance for the impartial judge, Emma. The girls suddenly start to worry about their mashup.
Ken confides in Terri that he thinks Emma is in love with Will. Desperate, Terri persuades him to propose to Emma. Ken does it.With the girls' confidence low, Kurt lets them know that boys took pills to boost their get-up-and-go. To even the playing field, the girls take the same pills from Terri. They give a high-spirited mashup performance. Will is oblivious to their newfound energy.
Emma asks Will if she should marry Ken. Later, Terri warns Emma that she has no chance with Will. Emma accepts Ken's proposal.Quinn agrees to give Terri her baby.
Rachel and Finn decide to nullify the mashup competition. When he learns about the pills, Principal Figgins fires Terri. Figgins also appoints Sue as co-director of the glee club.