Set in ancient Egypt under Roman rule, "Agora" follows the brilliant and beautiful astronomer Hypatia (Weisz) who leads a group of disciples fighting to save the wisdom of the Ancient World, as violent religious upheaval spills into the streets of Alexandria. Among these disciples are two men competing for her heart: the witty, privileged Orestes (Isaac) and Davus (Minghella), Hypatia's young slave, who is torn between his secret love for her and the freedom he knows can be his if he chooses to join the unstoppable surge of the Christians.