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Shakira, Drake, and Marc Anthony also join the winners at the April 30 ceremony, while Carlos Santana is among the special honorees.
The Alejandro Perez-directed video featuring scantily-clad ladies at an underground party was also made to promote the region Galicia in Spain.
The music video showcases Enrique and Pitbull as puppets who have fun on the street of Los Angeles just like normal human beings.
Calle 13 becomes the biggest winner at the event, setting record for the most Latin Grammy wins with 21.
The tour will open on September 12 in Newark, New Jersey, and will conclude on October 25 in Hollywood, Florida.
The track, which was premiered on Graham Norton's BBC Radio 2 on February 15, will be featured in the two singers' upcoming albums.
The clip, directed by Collin Tilley, shows Iglesias and Pitbull partying with a lot of girls who dance and twerk to the song.
The Colin Tilley-directed video sees the Latin singer getting emotional after finding out that his girlfriend is cheating on him.
After being away from the limelight for some time, the sexy singer-songwriter is back with a new steamy video featuring Sammy Adams.
Jennifer Lopez and Enrique Iglesias kick off their co-headlining tour in Canada beginning with Montreal.
The rumors are true, the 'X Factor (US) judge will lead the July 22 live show, replacing last year's Kaley Cuoco.
Stellar list of performers from different genres will take the stage at Las Vegas' MGM Grand this fall.
J.Lo spills one of the special treats she and her tour collaborator are preparing for concertgoers, saying, 'We're actually working on this really good song, a new song right now.'
After YouTube removed the video for violating its policy on sexual content, fashion photographer Terry Richardson, who directed the clip, gives fans a taste of Upton's sexy dance via Vimeo.
J.Lo points out the element that makes the tour different from any other gig, 'I don't think that there has ever been something like this that these Latinos have come together like this.'