Dan (Paul Johansson) must face the harsh consequences of his decision to murder Keith as Karen (Moira Kelly) and Haley's (Bethany Joy Galeotti's) pregnancies complicate the lives of Nathan (James Lafferty) and the graduating seniors of Tree Hill High.

Lucas (Chad Michael Murray) wrestles with his post-high school options, and Peyton (Hilarie Burton) and Brooke (Sophia Bush) prepare to spend the summer in Los Angeles together.