An updated version of the popular 1990s series, the lives and relationships of a diverse group of 20-somethings intertwine to form a close-knit surrogate family. Heading up this group is landlady Sydney Andrews (Laura Leighton, the original "Melrose Place"), still beautiful and a central figure in the lives of all her tenants, especially handsome and rebellious David Breck (Shaun Sipos, "Shark"), the estranged son of her former lover Dr. Michael Mancini (Thomas Calabro, the original "Melrose Place").

Other tenants include up-and-coming publicist Ella Simms (Katie Cassidy, "Harper's Island"), Auggie Kirkpatrick ("All My Children"), a successful sous chef at the trendy restaurant Coal with a dark past, Lauren Yung (Stephanie Jacobsen, "Terminator: The Sarah Connor Chronicles"), a medical student in desperate need of money to pay her student loans, and Jonah Miller (Michael Rady, "Swingtown"), an aspiring filmmaker who has just proposed to his live-in girlfriend Riley Richmond (Jessica Lucas, "Cloverfield"), a first-grade teacher.

The newest tenant, wide-eyed 21-year-old Violet Foster (Ashlee Simpson-Wentz, "7th Heaven"), has just arrived in LA and is horrified to find a bloody body floating in the courtyard pool. Suddenly everyone is a suspect.