Grey's Anatomy

Episode 2.12 : Grandma Got Run Over By A Reindeer

Grey's Anatomy Poster

TV Info

Episode Premiere

December 11, 2005




Drama, Comedy, Romance

Show Period

2005 - now

Production Company

Mark Gordon Co., Touchstone TV, ShondaLand

Cast and Crew


Peter Horton


Krista Vernoff

Main Cast

Additional Cast

  • Alex Stamm
  • C.J. Sanders
  • Richard Jenik
  • Jenny O'Hara
  • Kathe E. Mazur
  • Michael Hyatt
  • Sean McDermott


A young boy needs a heart transplant but doesn't seem to want it, and an argument over his treatment exposes major philosophical differences between Burke and Cristina he's spiritual, she's not. Burke won't operate on the boy until his mind accepts the heart, because he believes the body will reject it if he doesn't. Cristina, though not a believer, makes a connection with the kid over their shared skepticism, and gets the boy to want the heart. Meanwhile, when the interns rally to help Alex prepare to re take his exam, Izzie feels betrayed (after all, Alex just cheated on her). Meredith has to remind Izzie of the true spirit of the Christmas holiday.

Derek and Izzie treat a father who has a major attitude change after brain surgery the family thinks that Derek may have broken their dad, and Izzie doesn't necessarily disagree. George and Bailey deal with a woman needing minor surgery that keeps getting her surgery delayed. The woman's family is loud, obnoxious, and crazy, and George has to really stand up to them at the end. As for Derek, despite a reconciliation with Addison, Derek isn't in a festive mood. Christmas is about being with the one you love, and he doesn't think he's with that person.

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