There's hope for Meredith and Derek. Derek says Addison is leaving. He shows Meredith the divorce papers that Addison gave him to sign. Meredith's mother is still in the hospital but keeps escaping from her room, thinking she's still a doctor. Meredith wonders/fears if she's anything like her mother. Richard depends on George to watch out for Ellis. One of Bailey's very first patients one with Cystic Fibrosis returns to the hospital. Bailey is very attached emotionally to this patient and has a tough time when he dies in surgery. Cristina is a terrible patient. She steals charts from nurse's station and rounds with the other interns until Bailey sends her back to her room. Cristina's mother is the antithesis of Cristina. When Burke gets Cristina alone, he says he had a right to know about the pregnancy. Alex asks Izzie out on a date. Alex didn't pass the clinical skills portion of his medical boards. He has four months to take it again and pass or he's out. Izzie and Alex meet at Joe's to go on their first date, but Alex is in a foul mood.

Ellis kisses Richard. George does what Richard can't bring himself to do he restrains Ellis' wrists to the hospital bed. Finally, Cristina completely breaks down and can't stop crying: "Someone please sedate me!" Burke gets into Cristina's bed, comforting her. Addison puts on her wedding ring in front of Meredith: She's not leaving Seattle if there's the slightest chance Derek wants her back. At the end of the day, Meredith sees the divorce papers unsigned in Derek's bag.