In Season 3, Dr. Shaun Murphy (Freddie Highmore), a young surgeon with autism and savant syndrome, continues to use his extraordinary medical gifts at St. Bonaventure Hospital's surgical unit. As his friendships deepen, Shaun works harder than he ever has before as he starts dating, while navigating his environment and relationships to prove to his colleagues that his talents as a surgeon will save lives.
Following what he believes was a disastrous first date with Carly, Dr. Shaun Murphy proposes a radical surgery to save a newlywed woman's life. Meanwhile, after the new chief of surgery, Dr. Audrey Lim, announces that the residents can lead surgeries, Dr. Morgan Reznick and Dr. Alex Park compete for the chance to operate on an elderly patient who has been diagnosed with cancer.