"There's a song with Uzi that's really, really cool that we did with Pharrell," he told Spotify's "Rock This with Allison Hagendorf" podcast.
"I mean, it's not like Blink's making a rap song or anything. It's like bringing Uzi over to our world. So it's more of a punk kind of like reggae-feeling song."
"I don't think Blink will ever be anything but a pop-punk band," Barker added. "That's who we are, and I feel like our fans have journeyed with us when we've done songs like 'Miss You' or ballads like 'Adam's Song'."
Uzi isn't the first rapper Blink-182 have worked with - they previously collaborated and toured with Lil Wayne, while Barker has worked with hip-hop star Trippie Redd, executive producing his new project "NEON SHARK vs. Pegasus".
The new Blink-182 album, the follow-up to 2019's "Nine", will also include a tune with singer Grimes, which Barker describes as "really, really cool".
The rockers are currently working to complete the project, ahead of a release later this year (2021).