The 34-year-old actress took offence when the 38-year-old funnywoman made reference to recent speculation that Jameela suffers from Munchausen syndrome - which causes sufferers to insist they are sick when they are not.
Taking to Twitter on Friday (March 06), Michelle posted: "Place your bets on who will be the first famous person to get Corona." However, she then added: "Jameela doesn't count."
The coronavirus has seen more than 102,000 cases registered worldwide, with close to 3,500 fatalities. But Michelle's jibe provoked a furious response from Jameela, who hit back: "May you never suffer from chronic illness. May you never wake up in pain and swollen every f**king day of your life."
"May you never struggle with an invisible disability. May you never be laughed at over it by people who have never met you."
Refusing to back down, Michelle retorted, "I HAVE FINALLY MADE IT. Learn to LOL about yourself girl, it's freeing," as the actress fired back, "Congratulations on making fun of my chronic pain and illness. Big day for you."
Michelle appeared to put an end to the spat, though, as she concluded: "I never even brought them (chronic pain and illness) up. But well done turning it back around, you're truly a pro."
Jameela frequently speaks about her multiple health issues, including congenital hearing loss and labyrinthitis, hypermobile Ehlers-Danlos syndrome, and coeliac disease.