Hours after the couple confirmed it had parted ways, Camp moved to make the separation official.
She lodged legal papers in a U.S. court on Friday afternoon (April 19), according to The Blast.
In a joint statement addressing the split news, the pair wrote, "We can confirm that we have decided to separate, and this decision was made mutually and amicably."
The stars, who do not have any children, tied the knot in September, 2016.
It has since also emerged that Anna and Skylar have placed their marital home on the market.
The Los Angeles property, which boasts four bedrooms and four bathrooms, was listed on Zillow on April 8 for $2.6 million (£2 million).