March 01, 2010 08:40:00 GMT
Beside the 'Two and a Half Men' star, there will also be Elijah Wood and James Woods in the same episode.
In the middle of his messy personal life, Charlie Sheen keeps his career intact by making a guest voice appearance on "Family Guy". The actor, who was accused of strangling his wife Brooke Mueller on Christmas vacation, is animated on the cartoon wearing his signature "Two and a Half Men" shirt.
Not only Sheen, the particular episode also features Elijah Wood and again, James Woods. The latter had appeared twice in the show, first in 2005's "Peter's Got Woods" and the second in 2008's "Back to the Woods". Like Sheen, Wood and Woods fill out the voices of their respective characters.
The episode, called "Brian Griffin's House of Pain", will air on March 21. Lois encourages Brian to submit his pilot script to a network. However, Woods will sabotage him.
On another news, Seth McFarlane, the creator of the series, will attend this year's Paley Festival and talk about his shows on March 9.