Known from the preview, "Supernatural" will take on a laid back episode called "It's a Terrible Life", presenting an alternative in Sam and Dean's lives should they become non-hunters. Three clips taken from the March 26 episode have been released as a sneak peek..
In their alternate lives, Dean is a corporate man who enjoys health drinks and listens to news radio vs. rock stations. He works at a company called Sandover Bridge & Iron Company alongside Sam who is in Tech Support. The two meet in an elevator and Sam asks Dean whether they know each other. They don't. Then the curious Sam asks Dean the next time they meet, whether Dean believes in ghost.
It seems as if the two do not know each other but after co-workers start committing suicide at an alarming rate, the two find themselves working side by side to solve the murders.