"Who Do You Love" is the life story of legendary record producer Leonard Chess, founder of Chess Records in Chicago, IL, the label that helped popularize blues music during the 1950s and '60s.

Leonard, a Jewish immigrant from Poland and the son of a junkyard dealer, is mesmerized by the Black music and culture that surrounds him. Leonard and his brother Phil, open a club called the Macomba, and gamble on producing "race records" with the help of bass player and songwriter, Willie Dixon. After initial failure, they find tremendous success with the extraordinary Muddy Waters. As Muddy Waters becomes wildly popular, Leonard and Phil Chess create Chess Records. Leonard's obsession with the music business strains his family life, but Leonard makes great efforts to make things right at home with his wife Revetta, and son Marshall. As his priorities are changing, so is the music world around him. The Chess brothers put blues on the map as it radically reinvented itself as Rock 'n ' Roll.