The singer, 33, took to social media to share a clip of the tune, alongside footage of herself performing the new track blended with scenes from the classic film.
"I've been bored at home so I made a song for u animals!!! And a little video," she explained. "It's called HOME ALONE... dedicated to all of you sexy people hanging at home.....alone. and also dedicated to the one and only @culkamania."
The video begins with a clip of Daniel Stern's character Marv and Culkin's Kevin, saying "hello," as he points a gun into the camera. Kesha then dances around her lavish home in her bra, underwear, knee-high socks and a nearly unbuttoned blue denim shirt, showing off her kitchen, bedroom, and staircase.
"You know I'm home, alone / Macaulay, 'Caulay Culkin / And boo, I'm bored / My cellular is broken," she sings over a drum-heavy beat. "I'm in the mood, I'm in the zone / Honey, I'm not joking / Now ring me up on my home telephone, ring."
"I'm setting booby traps in case you're a bad guy / I'm reading bookies, baking cookies in my thigh-highs."
She ends the ditty with the line, "We'll have a fun time, fun time, right?"