Snipes has sealed a deal to play villain General Izzi in the film, according to The Hollywood Reporter.
The character rules an African nation that neighbours the one Eddie's Prince Akeen oversees.
Arsenio Hall is already on board to reprise his role as Semmi in "Coming 2 America", while James Earl Jones is also part of the cast. The new movie, which follows Prince Akeen as he returns to America to find his long-lost son, will be directed by Craig Brewer, who led "Hustle & Flow".
"Coming 2 America" begins filming this fall (2019) and is set for a 2020 release.
"To all the DAYWALKERS losing their minds right now, chillaaxx (sic)," Wesley told ComicBook.com. "Although the news comes as a surprise, it's ALL GOOD. Such is the 'business' of 'entertainment!' Much peace to the MCU crew - always a fan."
"Congratulations and Salaam (peace) to Mahershala Ali, a beautiful and talented artist whose expressions I look forward to experiencing for many years to come. Inshallah (God willing), we will someday work together."