Clark (Tom Welling) faces a surprising new foe in the form of a shy high school girl (guest star Brianna Lynn Brown) who turns to plastic surgery to enhance her looks and boost her popularity. However, things go awry when she discovers that her kryptonite - enhanced beauty causes harm to anyone she kisses - and she decides her next victim will be Lana (Kristin Kreuk). Meanwhile, Jason (Jensen Ackles) and Lana continue to hide their relationship from Clark.