Starring Diego Boneta (Scream Queens), Jackson Rathbone (Twilight) and newcomer Maria Mesa, "City of Dead Men" follows Michael (Boneta), an American tourist named recently arrived in Medellin, Colombia, where he discovers he's run completely out of money.

Desperate for a quick fix to the problem, he meets a young Colombian girl (Mesa), who introduces him to a group of misfits and their mysterious leader (Rathbone), who live in an abandoned psychiatric hospital.

At first accepting their friendship and shelter, it soon becomes clear something terrible happened in the hospital. The group living there now only feel immortal, pulling Michael into a dangerous dynamic that might kill him.