The pair will perform an MTV Unplugged gig, during which they'll belt out songs from their new standards album.
"Come witness a new chapter in Unplugged's history as Tony Bennett and Lady GaGa grace the Unplugged stage for the first time, performing fresh renditions off their brand new Jazz standards album - and a handful of surprises you definitely won't want to miss," a press release reads.
The show is set to be recorded at an undisclosed New York location and all audience members are required to be fully vaccinated.
The performance comes four months after 94-year-old Bennett's Alzheimer's diagnosis was unveiled in an interview with AARP in February.
Bennett's wife, Susan, said at the time, "There's a lot about him that I miss." She added, "Because he's not the old Tony anymore … But when he sings, he's the old Tony."
In the wake of the interview's publication, Bennett turned to Twitter to share, "Life is a gift - even with Alzheimer's. Thank you to Susan and my family for their support, and AARP." He continued, "The Magazine for telling my story."
The crooner learned he was battling the degenerative disease of the brain four years ago, but only began showing real signs of decline in 2018, when he began to record the follow-up to "Cheek to Cheek", his 2014 album with Lady GaGa, which will be released in the spring (2022).