They will join leading lady Milla Jovovich in the film, based on the popular Capcom video game, in which players track down and kill various monsters.
Milla's husband, Paul W.S. Anderson, will direct the project from a script he also wrote.
Details regarding the plot remain unknown, but production is due to begin in South Africa next month.
Jovovich and Anderson have already experienced huge success adapting a cult Capcom game for Hollywood after working together on the "Resident Evil" film franchise. The action-horror series debuted in 2002 with Milla as protagonist Alice, and concluded with a sixth instalment, titled "Resident Evil: The Final Chapter", in 2016, banking over $1.2 billion at the global box office. It is now reportedly in the process of being rebooted with a new lead actress.
Meanwhile, "Monster Hunter" marks the latest big film gig for T.I. after joining the Marvel Cinematic Universe in 2015 with a role in Paul Rudd's "Ant-Man" as one of the titular character's sidekicks. He reprised his part as Dave in this year's sequel, "Ant-Man and the Wasp".