The trio lead an all-star ensemble for the DreamWorks cartoon action-comedy, which is slated for release in April 2022.
The story centres on a criminal crew of animal outlaws as they attempt their most challenging crime yet - becoming model citizens.
The motion picture is being adapted from the Scholastic book series by Aaron Blabey and will mark Pierre Perifel's feature directorial debut. Perifel has previously worked as an animator on the hit movies "Kung Fu Panda" and "Shrek Forever After".
Etan Cohen is writing the script for the movie with Damon Ross and Rebecca Huntley producing. Blabey, Cohen and Patrick Hughes are serving as executive producers.
"Swan Song" is described as a genre-bending drama set in the near future that explores how far someone will go, and how much they'll sacrifice, to make a happier life for the people they love.
The "Crazy Rich Asians" star will play the character of Kate, the close friend and confidant of Ali's Cameron character while Harris is playing Poppy, Cameron's wife and true soulmate.
The project has been written and directed by Benjamin Cleary and is being produced by Adam Shulman, Jacob Perlin and Jonathan King. Ali is also serving as a producer through his Know Wonder banner.