As the pair took the debate stage for a final time at Belmont University in Nashville, Tennessee on Thursday (22Oct20) night, it was Biden who appeared to elicit the most favourable response from viewers, after Trump called New York a "ghost town" and referred to Europe as a "country."
"Wow. Even by Trump standards, this is an embarrassment for him," wrote Billy Eichner as Milano publicly endorsed Biden on her Twitter page, writing that the politician, "cares about American lives and their livelihoods.
"Trump doesn't care if we live or die," she insisted. "Therein lies the fundamental difference between Biden and Trump."
Added Aduba, "I don't look at this in terms that he does: blue states and red states. It's The United States' @JoeBiden is running to unite this country that has been ripped at the seams."
"Trump send love letters to North Korean dictator, he takes the word of Putin and of the Saudi murderer MBS as they kill our journalists and taking out bounties on our military men and women," wrote Marvel star Mark Ruffalo as John Cusack asked, "Ok - you saw this man lie for 1 hour 30 minutes. Have you had enough of this monster ? Are you done ?"
Meanwhile, it was Trump's apparent errors that left a number of stars in disbelief, with Turner sharing a snap of herself laughing as she watched along with the caption, "He called Europe a country."
However, Trump did have a handful of supporters, with Kirstie Alley writing, "TRUMP!! Doing great!!! Going great!! Steady as you go!!! GREAT JOB!!" She later added, "You are on fire on this one Mr. President!! He just Lost.. he's toast."