(*): W=Win, N=Nomination
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 1998 | N | Best Supporting Actress | Tomorrow Never Dies (1997) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2005 | N | Outstanding Lead Actress in a Comedy Series | Desperate Housewives (2004) (TV) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2005 | W | US TV Actress of the Year | Desperate Housewives (2004) (TV) | - |
| 2005 | W | - | - | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 1996 | W | Female Discovery of the Year | - | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2006 | N | Best Performance by an Actress in a Television Series - Musical or Comedy | Desperate Housewives (2004) (TV) | - |
| 2005 | W | Best Performance by an Actress in a Television Series - Musical or Comedy | Desperate Housewives (2004) (TV) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2011 | N | Favorite Web Celeb | - | - |
| 2006 | N | Favorite Female Television Star | - | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2008 | N | Performance in a Comedy Series | Desperate Housewives (2004) (TV) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 1997 | N | Worst Supporting Actress | Heaven's Prisoners (1996) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2005 | N | Best Actress in a Series, Comedy or Musical | Desperate Housewives (2004) (TV) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2008 | N | Outstanding Performance by an Ensemble in a Comedy Series | Desperate Housewives (2004) (TV) | Felicity Huffman, Marcia Cross, Eva Longoria, Nicollette Sheridan |
| 2007 | N | Outstanding Performance by an Ensemble in a Comedy Series | Desperate Housewives (2004) (TV) | Felicity Huffman, Eva Longoria, Marcia Cross |
| 2006 | W | Outstanding Performance by an Ensemble in a Comedy Series | Desperate Housewives (2004) (TV) | Marcia Cross, Eva Longoria, Felicity Huffman |
| 2005 | W | Outstanding Performance by a Female Actor in a Comedy Series | Desperate Housewives (2004) (TV) | - |
| 2005 | W | Outstanding Performance by an Ensemble in a Comedy Series | Desperate Housewives (2004) (TV) | Andrea Bowen, Ricardo Antonio Chavira, Marcia Cross |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2017 | N | Choice TV Villain | Supergirl (2015) (TV) | - |
| 2006 | N | TV - Choice Actress | Desperate Housewives (2004) (TV) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2005 | N | Individual Achievement in Comedy | Desperate Housewives (2004) (TV) | - |
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