In order to lure a vengeful vampire hunter named Rayna Cruz (guest star Leslie-Anne Huff) away from his friends in Mystic Falls, Stefan (Paul Wesley) heads to New Orleans, where Valerie (guest star Elizabeth Blackmore) has learned of a safe house that can protect him. Once there, he comes face to face with Klaus Mikaelson (guest star Joseph Morgan), who soon becomes suspicious of his old friend's unexpected arrival in his city.
Meanwhile, Enzo (Michael Malarkey), who is working on behalf of a mysterious organization called The Armory, approaches Damon (Ian Somerhalder) and Bonnie (Kat Graham) with a plan that could protect Stefan from Rayna. Finally, after learning that Alaric (Matt Davis) has decided to leave for Dallas with the twins immediately, Caroline (Candice King) offers to accompany them on the trip and finds herself contemplating her own future in Mystic Falls.
