The Big Bang Theory Episode 3.18 The Pants Alternative

Sheldon finds out he is being honored with a prestigious award by the University and suddenly gets stage freight and wants to decline the award just so he won't have to stand in front of his colleagues and give a speech. Penny wants to help Sheldon regain his confidence and enlists the guys to help her do it. She convinces Sheldon to allow them to help by comparing them to the "X-Men" team, which Sheldon gets in to and calls his team the "C-Men," which the guys hate. Penny takes Sheldon to buy a professional suit, while Leonard and Koothrappali try to provide psychological and spiritual guidance without much success. On the night of the event, Sheldon initially appears composed but soon his nerves get the best of him and as he is about to be introduced to the stage, he wants to run out. Penny gives him the only thing she knows will calm him down and get him through this speech - alcohol, and lots of it.