AceShowbiz - John Mulaney had to change the focus of Wednesday's episode of "Everybody's Live With John Mulaney" due to unforeseen events. The death of Pope Francis on Monday led to a quick pivot from the planned topic of "The Pope is still alive" to something completely different: dinosaurs.

Mulaney delved into his doubts about the existence of these prehistoric creatures, a subject that arose while reading a book to his three-year-old son. "I started to get a little creeped out because, like, I'm his main source of information. I'm his most trusted name in news, and I'm telling him, 'These are the dinosaurs,' " Mulaney explained to his audience.

Reflecting further, he mused, "And I don't mean this in any kind of Christian or political way, but are these things real? They don't sound real."

The comedian then invited his audience to critically examine the central premise of dinosaurs. "There were a bunch of giant lizards. Some were mean and some were not, and they ruled the world. And then they all died at once … That sounds like how a lie ends," Mulaney joked, poking fun at the established narrative about dinosaur extinction.

While addressing the scientific explanation for the dinosaurs' extinction, the comedian joked about the death of Gene Hackman and his wife Betsy Arakawa. "Scientists are now like, 'We believe the dinosaurs were killed 66 million years ago by an asteroid. Stop. You don't know that. We don't even know how Gene Hackman and his wife died."

He continued, "We found their whole bodies with full clothes on, one week after the event. How about that Santa Fe police? 'Uh, hello. Press conference No. 470. We now believe that a rat bit Mrs. Hackman, turning her hands into mummy hands.' Just slow down. You don't know what happened."

The audience gave mixed reactions ranging from gasps of shock to laugh, and the comedian was aware that his monologue might spark controversy. "It does feel weird to talk about anything anti-science right now," he said. "It's very politicized."