Actress Wendy Moniz recently filed for divorce in a Los Angeles court, listing their date of separation as February 21.
According to People.com, she is seeking joint legal and physical custody of their two children, Liam, 15, and 10-year-old Rio Joseph.
The former couple wed in October, 2000 after meeting on the set of U.S. soap opera "Guiding Light" in the late 1990s.
Grillo has yet to comment on the divorce news.
He also has 23-year-old son Remy from his previous marriage.