The media mogul launched this year's collections of must-haves on Friday, November 08 - and they feature makeup from Lady GaGa's Haus Laboratories line and a backpack designed by actress Sarah Jessica.
Introducing the items, which range from budget to luxury, in an online video, Oprah asked GaGa to show her how best to apply her makeup and Parker surprised the TV icon by stopping by to model her Carried Away Convertible Samsonite collaboration.
All 79 items, which also include desserts, sustainable goods and fashion accessories, will be featured in the December, 2019 issue of O, The Oprah Magazine.
Meanwhile, Oprah has given slimwear brand Spanx a huge endorsement after raving about the firm's new Perfect Black Pants.
"When I first saw these ultraflattering pants, I immediately called Sara Blakely, the founder of Spanx, to applaud her," Oprah wrote. "In sizes XS to 3X, they have built-in tummy control, so you don't need to wear compression gear underneath - you're already Spanxed!".