Khloe and her baby daddy Tristan have already weathered one cheating scandal, but news that the basketball star got close to Kylie Jenner's best pal spelled the end of their two-year romance.
Khloe, 34, has been making subtle digs about her ex and her former friend, with the latest involving the snake emoji.
"No matter how much a snake sheds its skin. It's still a snake," she posted on her Instagram Stories with a green snake accompanying the words.
She also told her 87.6 million followers, "People reveal themselves through their actions", and "If you want to make God laugh, tell him about your plans".
Not all of her posts were so sour though; the reality TV star also posted an uplifting message to her loyal fans.
"Just a reminder in case your mind is playing tricks today: you matter. You're important. You're loved. And your presence on this earth makes a difference whether you see it or not," the post read.
Neither Khloe nor 27-year-old Tristan, who share 10-month-old daughter True, have publicly commented on their split. However, 21-year-old Jordyn highlighted recent events during her first public appearance since the story broke.
Attending the launch of her new Eylure lash collaboration in Los Angeles, she told the crowd: "Through everything that's been going on, you know it's been real, and Eylure has been super real."
Jordyn has apparently been kicked out of the house she shared with Khloe's half-sister Kylie, and is said to have blamed her indiscretion with Tristan on being "blackout drunk", according to TMZ.com.