'Death Race 2' takes place in the very near future, as the United States economy begins to decline and violent crime starts to spiral out of control. To contain the growing criminal population, a vast network of for-profit, private prisons springs up, creating a lawless subculture ruled by gangs, cold-blooded killers and sociopaths. The worst of these prisons is Terminal Island.

Convicted cop-killer Carl Lucas (Luke Goss) arrives on the Island to serve his life sentence just as ruthlessly ambitious television personality September Jones launches the ultimate reality show, Death Race. A brutal prison yard demolition derby that pits prisoners against each other in steel reinforced, heavily armed vehicles, Death Race offers the winner the ultimate prize: freedom if he can survive to enjoy it. When Lucas signs up to be a driver, the stage is set for the birth of a legendary racer.