| Title | Star As | Genre | Info |
|---|---|---|---|
| Q-Force | Deb (voice) | TV | - |
| The One and Only Dick Gregory | Herself | - | - |
| The Upshaws | Lucretia / Lucretia Turner | TV | - |
| Title | Star As | Genre | Info |
|---|---|---|---|
| Breaking News in Yuba County | - | - | - |
| Friendsgiving | Fairy Gay Mother | - | - |
| Title | Star As | Genre | Info |
|---|---|---|---|
| Harley Quinn | (voice) | TV | - |
| Jexi | - | - | aka "Lexi" |
| Other Two, The | Shuli Kucerac | TV | - |
| The Wedding Year | - | - | - |
| UglyDolls | Wage (voice) | - | - |
| Title | Star As | Genre | Info |
|---|---|---|---|
| Hurricane Bianca: From Russia with Hate | Prison Matron | - | - |
| Title | Star As | Genre | Info |
|---|---|---|---|
| A Bad Moms Christmas | Dr. Karl | - | - |
| Snatched | Ruth | - | aka "Mother/Daughter" |
| Title | Star As | Genre | Info |
|---|---|---|---|
| Bad Moms | Dr. Karl | - | - |
| Dream Team | Leslie | TM | - |
| House of Lies | Rita | TV | - |
| Ice Age: Collision Course | Granny (voice) | - | - |
| What Happened Ms. Sykes? | Herself | TM | - |
| Title | Star As | Genre | Info |
|---|---|---|---|
| Black-ish | Daphne Lido | TV | - |
| How to Vajaculate: If You Build It, She Will Come | Goddess | - | - |
| Penn Zero: Part-Time Hero | General Shirley B. Awesome (voice) | TV | - |
| Title | Star As | Genre | Info |
|---|---|---|---|
| Alpha House | Senator Rosalyn DuPeche | TV | - |
| The Hot Flashes | Florine Clarkston | - | - |
| Title | Star As | Genre | Info |
|---|---|---|---|
| Bubble Puppy's Fin-tastic Fairytale Adventure | Witch | TM | - |
| Real Husbands of Hollywood | Wanda Sykes | TV | - |
| Title | Star As | Genre | Info |
|---|---|---|---|
| Ice Age: Continental Drift | Granny (voice) | - | - |
| Rio | Chloe (The Goose) (voice) | - | - |
| Title | Star As | Genre | Info |
|---|---|---|---|
| Back at the Barnyard | Bessy / Bessy the Cow | TV | - |
| Barnyard | Bessy | TV | - |
| Evan Almighty | Rita | - | - |
| Title | Star As | Genre | Info |
|---|---|---|---|
| Barnyard | Bessy the cow (voice) | - | - |
| Brother Bear 2 | Innoko (voice) | VI | - |
| Clerks II | Wife | - | - |
| CondomNation | Linda | - | - |
| My Super Ex-Girlfriend | Carla Dunkirk | - | - |
| Over the Hedge | Stella (voice) | - | - |
| The Adventures of Brer Rabbit | Sister Moon (voice) | VI | - |
| The New Adventures of Old Christine | Barb | TV | - |
| Title | Star As | Genre | Info |
|---|---|---|---|
| Monster-in-Law | Ruby | - | - |
| Title | Star As | Genre | Info |
|---|---|---|---|
| Wanda Does It | Wanda | TV | - |
| Title | Star As | Genre | Info |
|---|---|---|---|
| Curb Your Enthusiasm | Wanda | TV | - |
| Down to Earth | Wanda | - | aka Einmal Himmel und zurück (Germany) |
| Pootie Tang | Biggie Shorty | - | - |
| Title | Star As | Genre | Info |
|---|---|---|---|
| Nutty Professor II: The Klumps | Chantal | - | aka The Klumps (Australia) |
| Title | Star As | Genre | Info |
|---|---|---|---|
| Wanda at Large | Wanda Mildred Hawkins | TV | - |
| Title | Star As | Genre | Info |
|---|---|---|---|
| Tomorrow Night | - | - | - |
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