(*): W=Win, N=Nomination
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2012 | N | Best Performance by an Actor in a Leading Role | A Better Life (2011) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2012 | N | Favorite Movie Actor Supporting Role | - | - |
| 2011 | N | Favorite Movie Actor | A Better Life (2011) | - |
| 2009 | N | Outstanding Actor in a Comedy Series | Weeds (2005) (TV) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2011 | N | Best Actor (Mejor Actuacion Masculina) | Hidalgo - La historia jamas contada. (2010) | - |
| 2000 | N | Best Actor (Mejor Actor) | Sex, Shame & Tears (1999) | - |
| 1997 | N | Best Supporting Actor (Mejor Coactuacion Masculina) | Luces de la noche (1998) | - |
| 1997 | N | Best Actor (Mejor Actor) | Cilantro y perejil (1998) | - |
| 1995 | W | Best Actor (Mejor Actor) | 'Til Death (1994) | - |
| 1994 | N | Best Actor in a Minor Role (Mejor Actor de Cuadro) | La vida conyugal (1993) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2012 | N | Best Actor | A Better Life (2011) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2014 | N | Best Actor/Television | The Bridge (2013) (TV) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2012 | N | Best Male Lead | A Better Life (2011) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2003 | W | Best Bichir in a Film (Mejor Bichir en una Pelicula) | Don't Tempt Me (2001) | - |
| 2003 | N | Best Bichir in a Film (Mejor Bichir en una Pelicula) | Dark Cities (2002) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2013 | N | Best Actor | Savages (2012) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2012 | N | Outstanding Performance by a Male Actor in a Leading Role | A Better Life (2011) | - |
| 2009 | N | Outstanding Performance by an Ensemble in a Comedy Series | Weeds (2005) (TV) | Julie Bowen, Enrique Castillo, Guillermo Diaz |
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