"Greenleaf" centers on the journey of estranged daughter and disillusioned preacher Grace Greenleaf (Merle Dandridge, "The Night Shift") who has returned home after 20 years on the occasion of the mysterious death of her sister, Faith. As she reenters the world of Calvary Fellowship World Ministries, the Memphis megachurch run by her powerful parents Bishop James Greenleaf (Keith David, "Enlisted" and "Community") and Lady Mae Greenleaf (Lynn Whitfield, "The Josephine Baker Story"), it becomes evident that things are not as virtuous as they seem and that the family's outward display of faith hides sin and misdeeds.

In the series' second season, the Greenleaf family tree will split at the root as Jacob (Lamman Rucker, "Why Did I Get Married?") ventures off to begin his new career with long-time rival church Triumph Ministries, breaking faith with his father, Bishop James Greenleaf (Emmy-winner Keith David, "Community") while his mother, Lady Mae Greenleaf (Golden Globe nominee and Emmy-winner Lynn Whitfield, "The Josephine Baker Story"), struggles with Jacob's decision to abandon the family. Meanwhile, after exposing her Uncle Mac's (GregAlan Williams, "The Accountant") crimes, but failing to bring him to justice, Grace "Gigi" Greenleaf (Merle Dandridge, "The Night Shift") finds herself intrigued with someone new, Darius Nash (guest star Rick Fox, "Dope"), a local journalist who's been closely following the ongoing threats plaguing the Greenleaf empire.