Jane Villanueva (Gina Rodriguez) is a driven young woman studying to become a teacher, nursing a dream to be a writer, and supporting herself with a job at a hot new Miami hotel. All the years of watching telenovelas with the two women who raised her - her sexy, young-at-heart mother, Xiomara (Andrea Navedo) and her still-devout grandmother, Alba (Ivonne Coll) - have given Jane a slightly unrealistic view of romance, but her wonderful fiance, Michael (Brett Dier), is supportive and even understands her decision to "save herself" until marriage.
All of Jane's meticulous life plans are turned upside down, however, when she sees her doctor for a routine check-up and is accidentally artificially inseminated with a specimen meant for someone else. Now, Jane is faced with the most important decisions of her life - a life that has suddenly become as dramatic, complicated and unpredictable as the telenovelas she has always loved.
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