The "Welcome to the Jungle" hitmaker spoke with Guitars.com, where he addressed the possibility of new music from the band - admitting there's "no definitive answer on anything and I'll just keep to that".
"Stuff is happening, but there are no specifics," he added.
Reflecting on how releasing new music has changed for artists since the group's heyday, the star, real name Saul Hudson, added: "More than anything, it's because of the nature of the industry right now.
"It's just like, how do you want to do this? I mean there's material and there's recording and there's s**t going on, but we're not really sure what we're doing with it right now."
When the interviewer noted the music industry is "a lot different" than when the band released their last record, 2008's Chinese Democracy, which Slash was absent for, he agreed, adding, "There's a handful people who said, 'Yeah, make a record and go old school'. And there's a handful of people that are like, 'We don't even know what buying a record is anymore!'".
While there are no solid plans for new music, the "Paradise City" stars are heading to Europe later this year for a 13-date stadium and festival tour, beginning 20 May in Lisbon.