In a world where humanity's last hope for survival lies in the stars, a desperate mission unfolds in the gripping sci-fi epic Uprising. Directed by Bryan Singer and written by Marc Guggenheim, the film plunges viewers into a tense struggle for the future of the species. As a catastrophic threat looms over Earth, a diverse and conflicted crew, including determined scientist Leelee Sobieski, pragmatic engineer Hank Azaria, and idealistic leader David Schwimmer, is launched into the void. They are joined by seasoned veterans Jon Voight and Donald Sutherland, whose experience masks hidden agendas, while Stephen Moyer, Radha Mitchell, and Mili Avital navigate the personal and political fractures within their ranks.

The film masterfully builds a claustrophobic atmosphere of paranoia and suspense aboard the spacecraft, where the vast silence of space is shattered by internal discord and unforeseen perils. As the crew ventures further into the unknown, their unity is tested by secrets, conflicting motivations, and the immense psychological pressure of their impossible task. This character-driven thriller explores the limits of human endurance and the fragile alliances that must hold when the fate of everyone left behind hangs in the balance.