Piku (Deepika Padukone) juggles her life as a successful architect and being a single parent to her 70-year old father Bhashkor Banerji (Amitabh Bachchan). Getting a life of her own, just doesn't seem possible - not for the lack of trying but she's weighed down by the responsibilities of her work, home and a hypochondriac father.

While both are deeply attached with one another, they are equally strong headed, stubborn and just won't let go when dealing with each other's idiosyncrasies and quirks! When Bhashkor emotionally blackmails Piku to take a road trip from Delhi to native Calcutta, the owner of the local cab company Rana (Irrfan Khan) has no choice but to drive them personally since none of his drivers are willing to endure Piku or her eccentric father. During this crazy road trip they learn to deal with each other's moods and idiosyncrasies and it reveals more than Bhashkor's bathroom habits.

Piku is a heart-warming slice of life film about a father-daughter relationship where Bhashkor's irritating yet endearing demeanor and Piku's equally headstrong nature may always be at loggerheads but this seemingly dysfunctional relationship is bonded by an understated and an unconditional love that leaves you wanting more.