(*): W=Win, N=Nomination
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 1995 | N | Best Actress in a Leading Role | Little Women (1994) | - |
| 1994 | N | Best Actress in a Supporting Role | The Age of Innocence (1993) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2017 | N | Best Actress on a Television Series | Stranger Things (2016) (TV) | - |
| 1998 | N | Best Supporting Actress | Alien: Resurrection (1997) | - |
| 1993 | N | Best Actress | Dracula (1992) | - |
| 1992 | N | Best Actress | Edward Scissorhands (1990) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 1994 | N | Best Actress in a Supporting Role | The Age of Innocence (1993) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2000 | N | Favorite Actress - Drama | Girl, Interrupted (1999) | - |
| 1998 | W | Favorite Supporting Actress - Sci-Fi | Alien: Resurrection (1997) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 1995 | N | Best Actress | Little Women (1994) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2021 | N | Best Supporting Actress in a Limited Series or Movie Made for Television | The Plot Against America (2020) (TV) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2016 | N | Best Supporting Actress in a Movie Made for Television or Limited Series | Show Me a Hero (2015) (TV) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2017 | N | TV Performance of the Year - Actress | Stranger Things (2016) (TV) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2017 | N | Best Performance by an Actress in a Drama Series | Stranger Things (2016) (TV) | - |
| 1994 | W | Best Performance by an Actress in a Supporting Role in a Motion Picture | The Age of Innocence (1993) | - |
| 1991 | N | Best Performance by an Actress in a Supporting Role in a Motion Picture | Mermaids (1990) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 1990 | N | Best Female Lead | Heathers (1989) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 1995 | W | Best Actress | Little Women (1994) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2017 | N | Trending - Presented by Instant | "Winning SAG Awards Reaction" | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 1996 | N | Best Kiss | How to Make an American Quilt (1995) | Dermot Mulroney |
| 1994 | N | Best Kiss | Reality Bites (1994) | Ethan Hawke |
| 1993 | N | Best Kiss | Dracula (1992) | Gary Oldman |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 1993 | W | Best Supporting Actress | The Age of Innocence (1993) | - |
| 1990 | W | Best Supporting Actress | Mermaids (1990) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2011 | N | Performance in a TV Movie or Miniseries | When Love Is Not Enough: The Lois Wilson Story (2010) (TV Movie) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2003 | N | Worst Actress | Mr. Deeds (2002) | - |
| 2001 | N | Worst Screen Couple | Autumn in New York (2000) | Richard Gere |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2000 | W | - | - | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 1992 | W | Best Foreign Actress (Mejor Actriz Extranjera) | Edward Scissorhands (1990) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2010 | N | Best Actress in a Miniseries or a Motion Picture Made for Television | When Love Is Not Enough: The Lois Wilson Story (2010) (TV Movie) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2009 | W | Best Cameo | Star Trek (2009) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2018 | N | Outstanding Performance by an Ensemble in a Drama Series | Stranger Things (2016) (TV) | Millie Bobby Brown, Gaten Matarazzo, Finn Wolfhard |
| 2017 | W | Outstanding Performance by an Ensemble in a Drama Series | Stranger Things (2016) (TV) | Millie Bobby Brown, Gaten Matarazzo |
| 2017 | N | Outstanding Performance by a Female Actor in a Drama Series | Stranger Things (2016) (TV) | - |
| 2011 | N | Outstanding Performance by a Cast in a Motion Picture | Black Swan (2010) | Vincent Cassel, Mila Kunis, Natalie Portman |
| 2011 | N | Outstanding Performance by a Female Actor in a Television Movie or Miniseries | When Love Is Not Enough: The Lois Wilson Story (2010) (TV Movie) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 1997 | W | Female Star of the Year | - | - |
| 1990 | W | Female Star of Tomorrow | - | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 1994 | W | Best Supporting Actress | The Age of Innocence (1993) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2002 | N | Film - Choice Actress, Comedy | Mr. Deeds (2002) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 1989 | W | International Feature Film Competition (For the acting; Festival title: "Lethal Attraction") | Heathers (1989) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2000 | W | Motion Picture (On 6 October 2000, At 7018 Hollywood Blvd) | - | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 1990 | W | Best Young Actress Starring in a Motion Picture | Great Balls of Fire! (1989) | - |
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