Natasha Maria Hamilton was born on July 17, 1982, in Kensington, Liverpool, Merseyside, England. Before rising to prominence as a singer, she built the foundation of her performance career through local stage work and musical theater training in her hometown, developing the vocal abilities that would later define her time in one of Britain's most successful girl groups.

Hamilton's life changed in 1999 when she joined the girl group Atomic Kitten, replacing original member Kerry Katona. The group released their first single that same year and quickly established themselves as a chart force. Atomic Kitten went on to score three UK number one singles—"Whole Again" (2001), "Eternal Flame" (2001), and "The Tide Is High (Get the Feeling)" (2002)—alongside two UK number one albums, Right Now (2000) and Feels So Good (2002). Hamilton remained a constant presence in the lineup throughout the group's most commercially successful era, performing alongside Liz McClarnon and Jenny Frost.

When Atomic Kitten went on hiatus in 2008, Hamilton pursued solo projects, releasing the single "Ms. Emotional." She later reunited with her former bandmates for the reality series The Big Reunion in 2012, a program that brought several popular acts from the era back together and led to a renewed touring schedule for the group.

Beyond music, Hamilton expanded her profile as a television personality. In 2015, she appeared as a housemate on the sixteenth series of Celebrity Big Brother, and in 2023 she joined the cast of The Real Housewives of Cheshire. She continued performing with Atomic Kitten until departing the group in 2024, the same year she released the solo singles "Edge of Us" and "You Don't Know Me."

Since leaving Atomic Kitten, Hamilton has focused on her solo recording career, releasing a string of singles that culminated in her debut extended play, Extraction, in 2026. Her career arc—from Liverpool stages to chart-topping girl-group success and onward to reality television and independent solo work—has made her a durable figure in British pop culture.