(*): W=Win, N=Nomination
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 1999 | N | Best Actress | City of Angels (1998) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 1999 | N | Funniest Actress in a Motion Picture (Leading Role) | You've Got Mail (1998) | - |
| 1996 | N | Funniest Actress in a Motion Picture (Leading Role) | French Kiss (1995) | - |
| 1994 | W | Funniest Actress in a Motion Picture (Leading Role) | Sleepless in Seattle (1993) | - |
| 1990 | W | Funniest Actress in a Motion Picture (Leading Role) | When Harry Met Sally... (1989) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 1998 | N | Outstanding Individual Achievement for Voice Acting by a Female Performer in an Animated Feature Production | Anastasia (1997) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2008 | W | - | - | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2001 | N | Favorite Actress - Suspense | Proof of Life (2000) | - |
| 1999 | W | Favorite Actress - Comedy/Romance | You've Got Mail (1998) | - |
| 1999 | N | Favorite Actress - Drama/Romance | City of Angels (1998) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 1989 | W | Female Discovery of the Year | - | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 1999 | N | Best Performance by an Actress in a Motion Picture - Comedy/Musical | You've Got Mail (1998) | - |
| 1994 | N | Best Performance by an Actress in a Motion Picture - Comedy/Musical | Sleepless in Seattle (1993) | - |
| 1990 | N | Best Performance by an Actress in a Motion Picture - Comedy/Musical | When Harry Met Sally... (1989) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 1999 | N | Best Performance by an Actress in a Motion Picture - Comedy or Musical | You've Got Mail (1998) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 1994 | W | - | - | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 1989 | N | Best Female Lead | Promised Land (1987) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 1999 | N | Favorite Movie Actress | You've Got Mail (1998) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 1999 | N | Best On-Screen Duo | City of Angels (1998) | Nicolas Cage |
| 1995 | N | Best Female Performance | When a Man Loves a Woman (1994) | - |
| 1994 | N | Best Female Performance | Sleepless in Seattle (1993) | - |
| 1994 | N | Best On-Screen Duo | Sleepless in Seattle (1993) | Tom Hanks |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2009 | N | Worst Actress | The Women (2008) | Annette Bening, Eva Mendes, Jada Pinkett-Smith, Debra Messing |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 1995 | N | Outstanding Performance by a Female Actor in a Leading Role | When a Man Loves a Woman (1994) | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 1999 | W | Actress of the Year | - | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 2016 | W | - | - | - |
| Year | * | Category | Works | Shared |
|---|---|---|---|---|
| 1995 | W | - | - | - |
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