In a world where silence speaks volumes, A Sign of Affection follows Yuki Itose, a deaf college student who has built a quiet, self-sufficient life navigating the hearing world. Her world is turned upside down when she meets Itsuomi Nagi, a charismatic and multilingual senior who effortlessly communicates with her through sign language and written notes. As their connection deepens, Yuki must confront her own insecurities and the barriers she has constructed, while Itsuomi is drawn to her unique perspective and inner strength. The series delicately explores their budding romance, balanced with the everyday challenges Yuki faces and the support of her loyal friend, Rin. With a tender and heartfelt tone, this anime blends sweet romance with a thoughtful portrayal of disability, highlighting how love can transcend spoken language and foster genuine understanding between two very different souls.