Uncle Buck (Mike Epps) is a charismatic hustler who has gotten by on his charm for years. But when his brother Will and sister-in-law Alexis move to town and need help with their kids, he steps up to become their "manny". Their lives will never be the same.
Will (James Lesure) and Alexis (Nia Long) are wary of Buck's questionable parenting skills, but his unique perspective and street smarts provide some unconventional solutions to raising their three rambunctious kids, who typically make a hobby of terrorizing their nannies. Like most teenagers, Tia (Iman Benson) is resentful of her mother and feels neglected when Alexis starts a new job. Miles (Sayeed Shahidi) and Maizy (Aalyrah Caldwell) are wise beyond their years, each with their own common love of pushing boundaries and testing the adults in their lives.
Buck will attempt to apply his "know how" from the 'hood, as he transitions to his new life in the 'burbs. But it's definitely going to take more than hustle and charm to win over and earn respect from this family.